The Science Behind Mood Support Supplements: How Do They Work?

mood support

The burgeoning interest in mood support supplements is not without justification; as our understanding of mental health deepens, so does our curiosity about natural remedies capable of enhancing our mood holistically.

Here, we unravel the science behind popular ingredients found in mood support supplements and how they purportedly work. Let’s get started!

Omega-3 Fatty Acids

Long recognized for their heart health benefits, omega-3 fatty acids are also pivotal in mood regulation. This is found abundantly in fish oils, these fatty acids are components of cell membranes in the brain. These are instrumental in brain function.

Studies suggest that omega-3 supplements may ease symptoms of depression and anxiety. This is due to their anti-inflammatory effects. It can improve neurotransmitter pathways. What’s more, some studies even show that EPA and DHA found in omega-3 can be as effective as antidepressant medication.

B Vitamins

B vitamins are essential for the production of energy and neurotransmitters in the brain. These include vitamins B1, B2, B6, and B12. They play a crucial role in regulating mood. This is by maintaining healthy levels of:

  • serotonin
  • dopamine
  • GABA

Deficiencies in these vitamins have been linked to an increased risk of depression and other mood disorders. Supplementing with a high-quality B complex vitamin can help support overall mental well-being.


This adaptogenic herb has been used for centuries in Ayurvedic medicine. This is to promote calmness and enhance mood. It is believed to work by regulating the body’s stress response. This also helps to reduce cortisol levels.

High levels of cortisol, known as the “stress hormone,” have been linked to anxiety and depression. Participants who took a randomized controlled trial. They took Ashwagandha for eight weeks. They reported significantly lower levels of perceived stress, anxiety, and depression compared to those taking a placebo.

Ashwagandha may also help with cognitive function improvement performance. It can also show:

  • improved attention
  • reaction time
  • task performance

This is compared to those taking a placebo. Ashwagandha may also help with physical symptoms. This is related to stress and anxiety such as fatigue and sleep disturbances. Its adaptogenic properties have been shown to improve energy levels and aid in relaxation.


Another adaptogenic herb commonly used for its potential mental health benefits is ginseng. Ginseng has been traditionally used in Chinese medicine to promote vitality and longevity.

Research has shown that ginseng may have anti-depressant effects by increasing dopamine levels in the brain. Dopamine helps with neurotransmitter modulation. This is responsible for regulating mood, motivation, and reward.

St. John’s Wort

St. John’s Wort is an herbal remedy utilized for centuries. This helps to treat mental health conditions. The active ingredients in St. John’s Wort include hyperforin and hypericin. These are believed to increase the levels of neurotransmitters like serotonin and dopamine in the brain.

These neurotransmitters play a crucial role in regulating mood. Their increased presence is associated with improved emotional well-being. As a result, St. John’s Wort has been used to treat conditions such as depression and anxiety.


Chamomile is an herb that has been used for centuries. This is a natural remedy for stress and anxiety. The active compounds in chamomile include apigenin, luteolin, and bisabolol. These compounds have been found to interact with the brain’s receptors responsible for promoting relaxation.

Studies have shown that chamomile can help reduce symptoms of generalized anxiety disorder (GAD) and improve overall mood. It has also been found to be effective in treating insomnia and improving sleep quality.


Passionflower is another herbal remedy commonly used to promote relaxation and relieve feelings of stress and anxiety. This plant contains flavonoids and alkaloids that have been found to have a calming effect on the nervous system.

Research has shown that passionflower can help reduce symptoms of anxiety disorders, including GAD and panic disorder. It is also commonly used to improve sleep quality and treat insomnia.


Lavender is a popular herb known for its soothing scent and calming properties. The essential oil derived from lavender has been found to promote relaxation and decrease feelings of stress and anxiety.

Studies have shown that inhaling the scent of lavender can have an immediate calming effect on the brain, making it an effective tool for managing acute episodes of anxiety. It has also been found to help reduce symptoms of chronic anxiety disorders.


Magnesium, a vital mineral for numerous bodily functions, also has implications for our mental state. It assists in regulating the nervous system, which can help manage stress and prevent mood swings. Evidence suggests that magnesium deficiency is linked with higher levels of anxiety and depression,


L-Theanine is an amino acid predominantly found in green tea leaves. It’s well-regarded for promoting relaxation without drowsiness. This is a stark contrast to many pharmaceutical relaxants. The compound is believed to work by influencing neurotransmitters in the brain.

This helps enhance alpha brain waves associated with a relaxed but alert state.

S-Adenosylmethionine (SAMe)

SAMe is a compound naturally produced in the body that is involved in forming, activating, or breaking down other chemicals in the body. This includes:

  • hormones
  • proteins
  • drugs

Research indicates that SAMe can enhance mood. This is by fostering the production and regulation of hormones and neurotransmitters that influence mood.


The gut-brain axis is the biochemical signaling pathway. This is between the gastrointestinal tract and the central nervous system. This has recently gained attention for its role in emotional health. Probiotics, or beneficial bacteria, can influence this axis.

This leads to improved mood and cognitive function. The specific mechanisms are still being explored, but it is believed that these beneficial bacteria may help reduce inflammation and regulate neurotransmitter activity.

Make sure to also research about how the best womens probiotic could help with mood and emotional health. Mood probiotics supplements can reduce symptoms of depression and anxiety.

Discover the Science Behind Mood Support Supplements Today

In conclusion, the world of mood support supplements is vast and varied, with scientific investigations lending credibility to traditional wisdom about certain herbs and nutrients. However, it’s pivotal to approach supplementation with caution, considering potential side effects and interactions with medications.

Always consult with a healthcare professional before starting any new supplement regimen. With the right advice and support, mood supplements can be a valuable tool in managing mental health, alongside a balanced diet, regular exercise, and other forms of therapy.

Did you find this article helpful? Check out the rest of our blogs!